Friday, September 13, 2019

Exchange your ideas, views & research work on Dental Forum 2020

Conference Series LLC Ltd is delighted to invite the Scientists, Dentists, Doctors, researchers & experts from the arena of Dentistry and Oral Health, to attend European Forum on Dental Practice & Oral Health (Dental Forum 2020) on March 06-07, 2020 at Rome, Italy.



Dental Forum 2020 is a specially designed cluster conference which consists of keynote presentations, Oral talks, Poster presentations, Workshops, Panel Discussions and Exhibitions, Young Researcher Forums (YRF), Best Poster Award, Industry academic interactive sessions, and Industry Presentations etc.
Regards

Baijnath Paswan | Program ManagerDental Forum 2020 | Conferenceseries llc ltdEmail : dentalhealth@globalconferenceseries.net | Contact no: +44 20 360 82897


Thursday, September 12, 2019

How babies absorb calcium could be key to treating osteoporosis in seniors

New research reveals the mechanism that allows breastfeeding babies to absorb large amounts of calcium and build healthy bones—a discovery that could lead to treatment for osteoporosis and other bone diseases later in life.


"We build our bone mineral density until we're early adults and then stop, so we think of osteoporosis as a disease of the elderly," said Megan Beggs, a pediatric dietitian and Ph.D. candidate in physiology at the University of Alberta who led the study.
"Really, it's a pediatric disease with consequences in old age, so understanding what's happening at these younger ages, when bones are being built, is critical."
The researchers identified calcium-absorbing channels in the lower two-thirds of the small intestines of breastfed infant mice in a paper published in the journal Cellular and Molecular Gastroenterology and Hepatology.
Previous work had revealed that in adult mammals, most calcium absorption takes place in the upper part of the small intestines, where food spends much less time.
"It seems to be pretty much the opposite is happening in infants," said Beggs.
Babies need to take in massive amounts of calcium in the first year of life to build the cartilage they are born with into the body's 206 bones. This mineral deposition continues at a lower rate until around age 25.
This is the first time the infant mechanism for absorbing calcium has been understood. U of A pediatric nephrologist Todd Alexander, Beggs' Ph.D. supervisor and senior author of the paper, said that's partly because women and children's health has not traditionally been the subject of medical study. He said the research required specially adapted lab equipment to perform experiments on the tiny intestines of genetically altered infant mice.
Alexander said understanding this mechanism could be the first step in reversing diseases that cause weak bones in humans.
"You can imagine that if you have someone who has poor bone health, such as an elderly person or a sick child in neonatal intensive care who has not been able to breastfeed, it would be very useful therapeutically to turn this pathway on for them," Alexander said.
The researchers said their future research will look at the mechanism in pigs, which are even closer physiologically to humans than mice, and they will test their hypothesis that it is a hormone in breast milk that is responsible for regulating the channels.
This Dental Forum 2020 Conference is based on the theme “A Comprehensive access to Modern Dentistry”.  Dental Forum 2020, Rome welcomes proposals and ideas from both Industry & Academia to be presented at this interactive platform.

Regards
Baijnath Paswan | Program ManagerDental Forum 2020 | Conferenceseries llc ltdEmail : dentalhealth@globalconferenceseries.net | Contact no: +44 20 360 82897

Monday, September 9, 2019

The unexpected dangers of gum disease

Gum disease is common and unpleasant, but, according to a growing body of evidence, it could also play a role in a surprising range of seemingly unrelated health problems.



Plaque — a sticky substance that contains bacteria — builds up on teeth. If it is not brushed away, the bacteria can irritate the gums.
The gums may then become swollen, sore, or infected; this is referred to as gingivitis.
In general, gum disease can be treated or prevented by maintaining a good oral health regime.
However, if it is left to develop, it can result in periodontitis, which weakens the supporting structures of the teeth.
Gum disease, which is also called periodontal disease, is widespread. According to the Centers for Disease Control and Prevention (CDC), almost half of adults in the United States have some degree of gum disease.
The mechanisms behind periodontal disease are relatively well-understood, and newer research shows that this health problem may play a role in the development of a number of other conditions, including Alzheimer's disease, cancer, and respiratory disease.
In this Spotlight, we will cover some of the surprising links between gum disease and disparate health issues.

Friday, September 6, 2019

Can we heal teeth? The quest to repair tooth enamel, nature's crystal coat : 





Tooth enamel is one of the hardest tissues in the human body. It acts as a protective layer for our teeth, and gives our smile that pearly white shimmer. But when enamel erodes, it can't regrow itself.

In a significant scientific breakthrough, researchers recently discovered a way to regrow human tooth enamel.
Scientists from China have invented a gel that contains mineral clusters naturally found in teeth. In partially acid-damaged teeth, the gel stimulates crystal regrowth to restore tooth enamel back to its original structure.
While the method is yet to be tested on people, one day this could mean saying goodbye to painful needles, the dreaded dentist drill, and even fillings.

What is tooth enamel?

Enamel is the outermost layer of our teeth, and protects our pearly whites from wear and tear. It also insulates us from feeling pain and sensitivity.
When this protective coat erodes, our teeth soften and become vulnerable to developing cavities (holes in the teeth) which may require dental treatment such as fillings.
Tooth enamel contains the same minerals, calcium and phosphate, found in bone. Unlike bone though, enamel contains relatively more mineral, and enamel crystals are arranged in a complex geometrical pattern.
Under a microscope, enamel crystals are shaped like long ribbons, or spaghetti strands. These crystal strands are assembled into clusters, like packets of dry spaghetti, orientated at 60 degrees to each other. The ribbon clusters, which weave together like honeycomb, are known as rods and inter-rods.
When destroyed, this weave is difficult to recreate, because the cells that form enamel die as our teeth emerge from our gums.

Thursday, September 5, 2019

Scientists uncover key new molecules that could help to tackle tooth loss and regeneration : 



Our teeth take thousands of bites per day, and understanding exactly what holds them in place and how is key to helping people live with their own teeth for longer.
Now new research published in the Journal of Dental Research has shed light on the science behind the formation of the periodontal ligament, which helps keep the tooth stable in the jawbone. This improved understanding will also help scientists work towards regenerating the tissues that support teeth.
The study, led by the Universities of Plymouth and Geneva, shows how a signaling pathway called Notch, which is known to be activated in stem cells and cancer, is important for periodontal ligament development. A signaling pathway describes how a group of molecules in a cell work together to control one or more cell functions, such as cell division or cell death. After the first molecule in a pathway receives a signal, it activates another molecule. This process is repeated until the last molecule is activated and the cell function is carried out.

Abnormal activation or inhibition of certain signaling pathways can lead to cancer and other conditions, including problems with tissue regeneration.
A key finding in the new study, which was conducted in rodent teeth, is that Lamin A, a cell nuclear protein, is a direct target of Notch pathway.
Lamin A is best known for its mutated form progerin, which causes fatal 'early aging' disease, Progeria syndrome—but by uncovering its involvement in periodontal ligament formation, scientists have better insight into how molecules function during tissue regeneration, and how the process could be affected during disease.
Corresponding author Dr. Bing Hu, Associate Professor of Oral and Dental Health Research in Peninsula Dental School at the University of Plymouth, said: "The periodontal ligament starts to properly hold the tooth in the jawbone when a tooth breaks out and becomes functional.
"Understanding the mechanisms of how periodontal ligaments develop and the molecules that assist the tissue becoming mature is really important for our understanding of tissue regeneration and repair.
"The next steps are for us to see if and how the molecules we have identified in this study can be translated into a human-only model and, in turn, how they are affected in both healthy and diseased conditions."
Dr. Hu is also part of the University's Institute of Translational and Stratified Medicine (ITSMed).
This research is a part of the MD-Ph.D. thesis of Dr. Balázs Dénes of the University of Geneva, entitled Post-emergent tooth eruption: eruption rate, periodontal ligament maturation and cell signaling, directed by Professor Stavros Kiliaridis.
Dr. Dénes said: "We believe that our findings are an important stepping stone to better dental treatments in situations involving the periodontal ligament, such as gum disease (periodontitis), tooth restoration by dental implants or orthodontic tooth movement."
The full study, titled "Notch coordinates periodontal ligament maturation through regulating Lamin A," is published in in the Journal of Dental Research.
How often should I get my teeth cleaned?

If you went to your dentist for a check-up and dental clean in the last year, give yourself a pat on the back. Not everyone loves the dentist, but research shows people who visit at least once a year for preventative care are happier with their smile.

Regular dental visitors are also less likely to need a filling or have a tooth removed.
So how often do we need to go to the dentist? Most of us can get away with an annual trip, but some people at higher risk of dental problems should visit more often.
Why do I need to get my teeth cleaned?
While we all do the best we can on our own, professional teeth cleaning removes plaque, the soft yellowish build-up, and calculus (hardened plaque) we can't get to. This soft build-up is made up of billions of different types of bacteria that live and reproduce in our mouth by feeding on the food we eat.
Most bacteria live in our bodies without causing too much trouble. But certain bacteria in dental plaque, when they grow in numbers, can lead to cavities (holes in the teeth) or gum disease.
A dental clean will reduce your chance of getting cavities or gum disease by significantly reducing the amount of plaque and calculus in your mouth.
So how often?
As a dentist, my patients often ask me how regularly they should get their teeth cleaned. My response is usually: "That depends."
Most private health insurance schemes cover a dental check-up and clean once every six months. But there's no hard and fast evidence, particularly if you're a healthy person who is less likely to get a cavity or gum disease.
However, some people are at higher risk of getting dental cavities or gum disease—and this group should get their teeth cleaned more often.
Hole in one
We know certain health and lifestyle factors can affect a person's risk of developing cavities. Here are some yes/no questions you can ask yourself to understand whether you're at a higher risk:
  1. is your drinking water or toothpaste fluoride-free?
  2. do you snack a lot, including on sweets?
  3. do you avoid flossing?
  4. do you brush your teeth less than twice a day?
  5. do you visit your dentist for toothaches rather than check-ups?
  6. do you need new fillings every time you visit the dentist?
  7. is your dentist "watching" a lot of early cavities?
  8. do you have to wear an appliance in your mouth such as a denture or braces?
  9. do you suffer from a chronic long-term health condition such as diabetes?
  10. do you suffer from a dry mouth?
  11. If you answered "yes" to most of these questions, you're likely to need to see your dentist or hygienist at least every six months, if not more often.

As well as removing the bug-loaded plaque and calculus, people prone to cavities benefit from the fluoride treatment after scaling.
Evidence shows professional fluoride treatment every six months can lead to a 30% reduced risk of developing cavities, needing fillings or having teeth removed.

Dental health is related to our overall health
Some people with chronic health issues such as heart conditions or diabetes will need to see their dentists more frequently. This is because they are more prone to gum disease.
People taking blood thinners and other medications, such as pills and infusions for osteoporosis, may need to visit the dentist more regularly too. These medications can complicate the process of an extraction or other dental work, so regular checks and cleans are best to help detect problems before they become serious.
People with bleeding gums should also see their dental practitioners more often. This is especially important if you have been diagnosed with advanced gum disease, known as periodontal disease.
What about the budget?
The average cost of a check-up, dental clean and fluoride treatment is A$231, but the cost can vary from A$150 to A$305. You can contact your local dentist to find out what they charge. Your dentist may offer you a payment plan.
If you can't afford this, you may qualify for free or discounted treatment if you hold a concession card. Children from families that receive a Family Tax Benefit A may be eligible for free dental treatment through the Child Dental Benefits Schedule.
People with private health insurance with extras or ancillary cover will also have some or all of their dental treatment covered.
Protecting your smile
So you don't really get cavities or have gum disease, but would prefer to see your dentist every six months? Great. Some people prefer to go twice a year to reduce the chance of a nasty toothache.
Parents often wish to set a good example for their children by making regular check and clean appointments for the whole family.
There are many benefits to regular checks and cleans. Visiting your dentist regularly helps reduce the chance of needing more complex and expensive dental treatment later on.
And touching base with your oral health practitioner provides that nudge we all need now and again to eat healthily, brush better and floss more often.

Tuesday, August 27, 2019

'No-drill' dentistry stops tooth decay

A new study has revealed that tooth decay (dental caries) can be stopped, reversed, and prevented without the need for the traditional 'fill and drill' approach that has dominated dental care for decades. The seven year study found that the need for fillings was reduced by 30 to 50 per cent through preventative oral care.

Conference Series LLC Ltd is delighted to invite the Scientists, Dentists, Doctors, researchers & experts from the arena of Dentistry and Oral Health, to attend European Forum on Dental Practice & Oral Health (Dental Forum 2020) on March 06-07, 2020 at Rome, Italy. Dental Forum 2020 is a specially designed cluster conference which consists of keynote presentations, Oral talks, Poster presentations, Workshops, Panel Discussions and Exhibitions, Young Researcher Forums (YRF), Best Poster Award, Industry academic interactive sessions, and Industry Presentations etc.
This Dental Forum 2020 Conference is based on the theme “A Comprehensive access to Modern Dentistry”.  Dental Forum 2020, Rome welcomes proposals and ideas from both Industry & Academia to be presented at this interactive platform.

Regards

Baijnath Paswan | Program ManagerDental Forum 2020 | Conferenceseries llc ltdEmail : dentalhealth@globalconferenceseries.net | Contact no: +44 20 360 82897